Antagonists of endothelin receptors

Details Antagonists of endothelin receptors Antagonists of endothelin receptors

C - Chemistry, Metallurgy

07

K

C07K 5/065 (2006.01) A61K 31/405 (2006.01) A61K 38/05 (2006.01) C07D 209/20 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2183767

The present invention provides novel compounds having pharmaceutical properties represented by general formula (I) wherein Ar represents a direct bond or arylene; processes for the manufacture, pharmaceutical compositions and the use of the compounds of formula (I) and salts thereof.

L'invention se rapporte à de nouveaux composés possédant les propriétés pharmacologiques représentées par la formule générale (I), ainsi qu'aux sels de ceux-ci. Dans cette formule, Ar représente une liaison directe ou arylène. L'invention se rapporte également à des procédés de fabrication des composés de la formule (I) et des sels de ceux-ci, aux compositions pharmaceutiques les contenant ainsi qu'à l'utilisation desdits composés et sels.

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