Antagonists of gm-csf derived from the carboxyl terminus

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/535 (2006.01) A61K 39/395 (2006.01) C07K 7/04 (2006.01) C07K 16/24 (2006.01) C07K 16/42 (2006.01) C12N 5/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2062975

2062975 9101330 PCTABS00003 Antagonists of GM-CSF are disclosed that comprise antibodies and anti-idiotypic antibodies specific for the carboxyl terminus of GM-CSF. These antagonists are useful for treating various diseases, the symptoms of which are increased by GM-CSF, and for lessening the effects of chemotherapy.

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