Antagonists of human gamma interferon

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/42 (2006.01) A61K 38/21 (2006.01) A61K 39/395 (2006.01) C07K 14/57 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2149785

2149785 9412531 PCTABS00032 Antagonists of human IFN-.gamma. are provided which are based upon a critical region of the human IFN-.gamma. receptor. Examples of such antagonists, which mimic, comprise or specifically bind to the critical region or the receptor, are polypeptides and antibodies or fragments thereof. Also provided are compositions and methods for inhibiting the biological activity of human IFN-.gamma..

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