Antagonists of protease activated receptor-1 (par1)

Details Antagonists of protease activated receptor-1 (par1) Antagonists of protease activated receptor-1 (par1)

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2657935

The present invention provides antibodies or antigen-binding molecules that specifically recognize and antagonize human PAR1 receptor. Also provided in the invention are polynucleotides and vectors that encode such molecules and host cells that harbor the polynucleotides or vectors.

La présente invention concerne des anticorps ou des molécules se liant aux antigènes qui reconnaissent et antagonisent spécifiquement un récepteur PAR1 humain. Cette invention concerne aussi des polynucléotides et des vecteurs codant pour ces molécules et des cellules hôtes qui accueillent ces polynucléotides ou ces vecteurs.

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