Antagonizing an adenosine a2a receptor to amelioriate one or...

A - Human Necessities – 61 – K

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A61K 31/522 (2006.01)

Patent

CA 2571242

This invention provides a method of mitigating/ameliorating one or more components of addictive behavior associated with chronic consumption of a substance of abuse, or withdrawal therefrom. The method typically involves administering to a subject in need thereof an adenosine A2A receptor antagonist in an amount sufficient to ameliorate said one or more components of addictive behavior.

Cette invention concerne un procédé d'atténuation/amélioration d'une ou plusieurs composantes du comportement addictif lié à la consommation chronique d'une substance donnant lieu à des abus, ou de son sevrage. Le procédé consiste généralement à administrer à un sujet en ayant besoin un antagoniste récepteur d'adénosine A2A en quantité suffisante pour améliorer un ou plusieurs composantes du comportement addictif.

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