Anthelmintic bioconversion products

Details Anthelmintic bioconversion products Anthelmintic bioconversion products

C - Chemistry, Metallurgy

12

P

195/129, 167/223

C12P 17/18 (2006.01) A01N 43/90 (2006.01) A61K 31/495 (2006.01) C07D 491/22 (2006.01)

Patent

CA 2013412

5/DLR13 17737 TITLE OF THE INVENTION ANTHELMINTIC BIOCONVERSION PRODUCTS ABSTRACT OF THE DISCLOSURE There are disclosed new compounds with significant antiparasitic activity which are prepared by fermenting the compounds paraherquamide or dihydroparaherquamide in a novel microorganism identified as Cunninghamella blakesleeana MF-4415. The paraherquamide compound is modified by the microorganism by ring hydroxylation or ketonization. The compounds are significant antiparasitic and anthelmintic agents and compositions for that use are also disclosed.

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