Anthelmintics

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/60 (2006.01) A01N 43/40 (2006.01) A01N 43/54 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) C07D 213/643 (2006.01) C07D 213/85 (2006.01) C07D 239/28 (2006.01) C07D 239/34 (2006.01) C07D 239/38 (2006.01)

Patent

CA 2026037

AP/5-17757/= Anthelmintics Abstract Anthelmintically active compounds of formula I are described Image in which R1 is hydrogen, halogen, C1-C2alkyl, C1-C2thioalkyl, C1-C2haloalkyl, nitro, C1-C2alkoxy, or the group SOnR in which R is C1-C2alkyl or phenyl and n is 0, 1 or 2; R2 is hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, C1-C2haloalkoxy or C1-C2alkoxy; R3 is hydrogen or C1-C2alkyl; R4 is hydrogen or C1-C2alkyl; R5 is hydrogen, halogen or C1-C5alkyl; R6 is hydrogen, halogen or C1-C5alkyl; R7 is hydrogen, halogen, C1-C2alkyl nitro, C1-C2haloalkyl, C1-C2halo- alkoxy or C1-C2alkoxy; R8 is hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, C1-C2haloalkoxy or C1-C2alkoxy; R9 is hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, C1-C2haloalkoxy or C1-C2alkoxy; R10 is hydrogen, halogen, C1-C6alkyl, C1-C2haloalkyl, C1-C2alkylthio, C3-C6cycloalkyl or cyano; R11 is hydrogen, halogen, C1-C6alkyl, C1-C2haloalkyl, C1-C2alkylthio or C3-C6cycloalkyl; R12 is hydrogen or halogen; and Y is =CH- or =N-; including the physiologically tolerable acid additionsalts thereof, and also the preparation and use thereof and novel inter- mediates.

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