Anthelmintics

Details Anthelmintics Anthelmintics

C - Chemistry, Metallurgy

07

D

167/234, 260/298

C07D 277/68 (2006.01) A01N 43/78 (2006.01) A61K 31/425 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2026090

AP/5-17758/= Anthelmintics Abstract Anthelmintically active compounds of formula I are described Image (I) in which R1 is hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, nitro, C1-C2alkoxy, or the group SOnR in which R is C1-C2alkyl or phenyl and n is 0, 1 or 2; R2 is hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, C1-C2haloalkoxy or C1-C2alkoxy; R3 is hydrogen or C1-C2alkyl; R4 is hydrogen or C1-C2alkyl; R5 is hydrogen, halogen or C1-C5alkyl; R6 is hydrogen, halogen or C1-C5alkyl; R7 is hydrogen, halogen, C1-C2alkyl, nitro, C1-C2haloalkyl, C1-C2halo- alkoxy or C1-C2alkoxy; R8 is hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, C1-C2haloalkoxy or C1-C2alkoxy; R8 is hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, C1-C2haloalkoxy or C1-C2alkoxy; R10 is hydrogen, halogen, nitro, NCS, OCF3, C1-C2alkyl or C1-C2alkoxy; R11 is hydrogen, halogen, nitro, NCS, OCF3, C1-C2alkyl or C1-C2alkoxy; or R10 and R11 together form a -O(CH2)mO- bridge in which m is 1, 2 or 3, including the physiologically tolerable acid addition salts thereof, and also the preparation and use thereof and novel intermediates.

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