Anthelmintics

Details Anthelmintics Anthelmintics

C - Chemistry, Metallurgy

07

D

167/222, 260/257

C07D 403/12 (2006.01) A01N 43/54 (2006.01) A61K 31/505 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2031156

AP/5-17858/+ Anthelmintics Abstract Novel anthelmintics are described, which contain as active ingredient acompound of formula I Image (I) or, in its hydrogenated form, formula Ia Image (Ia) wherein R1 and R2 are each independently of the other C1-C6alkyl, allyl, C3-C6- cycloalkyl, benzyl or phenyl; and R3 is an unsubstituted or substituted heteroaromatic five-membered ring azole, bonded via carbon, selected from the series benzimidazole, benzoxazole, benzothiazole, imidazole, oxazole, thiazole, oxadiazole, thiadiazole and triazole; and R4 and R5 are each independently of the other hydrogen, C1-C6alkyl, C1-C6haloalkyl, C1-C6- alkoxy or C1-C6haloalkoxy, including its tautomeric forms and physiologically tolerable salts. The preparation, formulation and use of these active ingredients is also described.

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