Anthracycline compound, process for production thereof, and...

C - Chemistry – Metallurgy – 12 – P

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195/90, 260/208.

C12P 19/56 (2006.01) C07H 15/24 (2006.01) C07H 15/252 (2006.01)

Patent

CA 1207692

ABSTRACT OF THE DISCLOSURE An anthracycline, serirubicin, of the formula: Image wherein R represents the substituent: Image is produced by a process which comprises cultivating a strain of Streptomyces in a suitable culture medium under aerobic conditions, said strain having the ability to produce the anthracycline compound, seri- rubicin, and then recovering the anthracycline compound, serirubicin, from the cultured medium. This seriru- hicin, or an acid addition salt of the serirubicin, can be contained as the active ingredient in anti- tumor agents and in pharmaceutical compositions for treatment of infections induced by gram-positive microorganisms, whereby good results are attainable.

446928

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