C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/24 (2006.01) A61K 31/70 (2006.01) C07D 221/18 (2006.01) C07F 7/08 (2006.01) C07H 15/244 (2006.01) C07H 15/252 (2006.01) C07H 15/26 (2006.01) C07H 17/02 (2006.01) C07H 23/00 (2006.01)
Patent
CA 2048510
S 5719-9 Can ABSTRACT This invention provides novel anti-tumour compounds of the formula Image wherein R1 and R2 axe hydrogen or together form an alkyl-, alkoxy- or OH-substituted aromatic group, which optionally contains an N atom as a hetero-atom; R is -OOCH3 or -C=C-R4 and R4 is H or trimethylsilyl; and R3 is H or -COCF3; and acid addition salts thereof; as well as composi- tions containing these compounds.
de Bie Joannes F. M.
de Vos Dirk
Scheeren Johan W.
Gowling Lafleur Henderson Llp
Pharmachemie B.v.
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