C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
195/91, 260/208.
C12P 29/00 (2006.01) C07H 15/252 (2006.01) C12P 19/56 (2006.01)
Patent
CA 1207694
ABSTRACT An anthracycline compound, ditrisarubicin, of the formula: Image wherein R represents one of the following substituents (A), (B), and (C): (A) Image (B) Image (C) Image is produced by a process which comprises cultivating a strain of Streptomyces in a suitable culture medium under aerobic conditions, said strain having the abi- lity to produce the anthracycline compound, ditrisaru- bicin, and then recovering the anthracycline compound, ditrisarubicin, from the cultured medium. This ditri- sarubicin, or an acid addition salt of the ditrisarubi- cin, can be contained as the active ingredient in antitumor agents and in pharmaceutical compositions for treatment of infections induced by gram-positive micro- organisms, whereby good results are attainable.
440171
Hamada Masa
Imoto Masaya
Naganawa Hiroshi
Sawa Tsutomu
Takeuchi Tomio
Fetherstonhaugh & Co.
Microbial Chemistry Research Foundation
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