Anthracycline derivative conjugates, process for their...

A - Human Necessities – 61 – K

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A61K 47/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2727915

The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.

La présente invention concerne des conjugués danthracyclines thérapeutiquement utiles avec des véhicules tels que des anticorps polyclonaux ou monoclonaux, des protéines ou des peptides dorigine naturelle ou synthétique, des procédés pour leur préparation, une composition pharmaceutique les contenant et leur utilisation dans le traitement de certaines tumeurs chez les mammifères.

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