C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
167/184, 260/208
C07H 15/252 (2006.01) A61K 31/71 (1990.01)
Patent
CA 2021911
- 1 - BEHRINGWERKE AKTIENGESELLSCHAFT 89/B 031 - Ma 786 Dr. Ha/Sd Abstract of the disclosure Anthracycline derivatives Anthracycline derivatives which have cytostatic activity and correspond to the formula I Image Formula I in which the radicals have the following meaning: R1 is H or OH, R2 is H, OH or OMe, R3 is H, OH or COOMe, R4 is COMe, COCH2OH, CH(OH)Me, CH(OH)CH2OH or C1-C2-alkyl, R5 is H, OH, O-tetrahydropyranyl or O-acetyl, R6 and R7 are C1-C4-alkyl and n is 1, 2 or 3, a process for the preparation thereof and the formulation thereof as pharmaceuticals, and the use thereof for the treatment of cancers, are described.
Dehmel Konrad
Gronau Thomas
Hoffmann Dieter
Kolar Cenek
Kraemer Hans P.
Behringwerke Aktiengesellschaft
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dehmel Konrad
Gronau Thomas
Hoffmann Dieter
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