Anthracycline derivatives, a process for the preparation...

Details Anthracycline derivatives, a process for the preparation... Anthracycline derivatives, a process for the preparation...

C - Chemistry, Metallurgy

07

H

167/182, 260/208

C07H 15/252 (2006.01) A61K 31/65 (2006.01) C12P 19/56 (2006.01)

Patent

CA 2019315

- 1 - Abstract of the disclosure: Novel anthracycline derivatives, a process for the preparation thereof and the use thereof as a pharmaceutical The present invention relates to anthracycline deriv- atives of the formula I Image (I) in which R1 is the sugar residue Roa or the combination of sugars Roa-Rod-Rod and R2 is the sugar residue Roa, Roa being rhodosamine of the formula II Image (II) and Roa-Rod-Rod being rhodosamine-rhodinose-rhodinose of the formula III Image (III) and the pharmacologically acceptable salts thereof, and - 2 - a microbiological process for the preparation thereof. The compounds have cytostatic activity and can therefore be used as pharmaceuticals.

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