Anthracycline derivatives for treatment of amyloidosis

C - Chemistry – Metallurgy – 07 – H

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Details

C07H 15/252 (2006.01) A61K 31/704 (2006.01) A61K 31/706 (2006.01)

Patent

CA 2176144

The present invention provides the use in the manufacture of a medicament for use in the treatment of amyloidosis of an anthracycline of formula A: wherein R1, R2, R3 and X are appropriate substituents. Novel compounds of the formula A, processes for their production and pharmaceutical compositions containing them are also described.

La présente invention se rapporte à la fabrication d'un médicament utilisé dans le traitement de l'amyloïdose, à partir d'une anthracycline de la formule (A) dans laquelle R¿1?, R¿2?, R¿3? et X représentent des substituants appropriés. De nouveaux composés de la formule (A), leurs procédés de production et leurs compositions pharmaceutiques sont également décrits.

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