C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/208.1
C07H 15/24 (2006.01) C07D 317/72 (2006.01) C07D 339/06 (2006.01) C07F 5/02 (2006.01) C07H 15/252 (2006.01)
Patent
CA 1174669
RAN 4060/110 ABSTRACT The invention provides compounds of the formula Image I wherein R represents a lower alkyl or carboxy group or a group of the formula Image a in which n stands for 1 or 2 and Y represents a hydrogen atom or an alkyl group and RY and RZ each represent a hydrogen atom or one of RY and RZ represents a hydrogen atom and the other represents a hydroxy group, and pharmaceutically acceptable acid addition salts thereof. These compounds and salts possess antibiotic and antitumour activity and can be used as medicaments in the form of pharmaceutical preparations.
380480
Broadhurst Michael J.
Hassall Cedric H.
Thomas Gareth J.
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
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