Anthracycline synthesis

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 50/36 (2006.01)

Patent

CA 1142177

ABSTRACT OF THE DISCLOSURE A process for synthesizing the 7-substituted or unsubstituted 2,5, 12-trihydroxy-1,2,3,4,6,11-hexahydro-2,6,11-trioxonaphthacene precursors for doxorubicin and related compounds from butadiene and p-benzoquinone and intermediates useful in the synthesis.

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