Anthracycline synthesis

C - Chemistry – Metallurgy – 07 – C

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C07C 50/22 (2006.01) C07C 41/26 (2006.01) C07C 43/21 (2006.01) C07C 43/215 (2006.01) C07C 43/225 (2006.01) C07C 43/23 (2006.01) C07C 45/69 (2006.01) C07F 1/02 (2006.01)

Patent

CA 1124234

ANTHRACYCLINE SYNTHESIS Abstract of the Disclosure A process for synthesizing the 7-substituted or unsub- stituted 5,12-dihydroxy-1,2,3,4,6,11-hexahydro-2,6,11- trioxonaphthacene precursors for doxorubicin and related compounds from butadiene and p-benzoquinone and intermedi- ates useful in the synthesis.

329085

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