C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 239/48 (2006.01) C07D 401/12 (2006.01) C07D 403/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2676257
The present invention relates to a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof; where R1, R2, R3, R4, r and s are as previously defined. Compounds of the present invention are useful in the treatment of diseases associated with Aurora kinase activity such as cancer.
Cette invention a trait à un composé de formule (I) suivante ou un de ses sels pharmaceutiquement acceptables, dans laquelle R1, R2, R3, R4, r et s sont tels que définis précédemment. Les composés de l'invention sont utilisés dans le traitement des maladies associées avec l'activité des Aurora kinases comme le cancer.
Axten Jeffrey Michael
Bryan Deborah L.
Drewry David Harold
Faitg Thomas H.
Gallagher Timothy Francis
Glaxosmithkline Llc
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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