Anthranilonitrile derivatives and related compounds as...

C - Chemistry – Metallurgy – 07 – C

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C07C 215/68 (2006.01) A23K 1/16 (2006.01) A23K 1/22 (2006.01) C07C 255/59 (2006.01)

Patent

CA 1276179

ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS ABSTRACT OF THE INVENTION There is provided a compound of the formula (I): Image (I) wherein R1 is ethyl, n-propyl, isopropyl, tert-butyl, 2-butyl, cyclobutyl or cyclopentyl; R2 is hydrogen or methyl; X is fluorine or chlorine; Y is hydrogen, methyl, fluorine, chlorine or bromine; Z is hydrogen, fluorine, chlorine or cyano; Q is hydrogen or NR3R4; where R3 and R4 are each independently hydrogen, methyl, ethyl, n-propyl or isopropyl; with the provisos that Y and Z cannot simultaneously be hydrogen; that when Y is hydrogen, X and Z cannot be chlorine; that when Q is hydrogen, Z is cyano; and that when Z is hydrogen, X is fluorine and Y is fluorine or chlorine; the optical isomers; and the parmacologically acceptable salt thereof. These are useful for promoting growth, improving feed efficiency and for increasing the lean meat to fat ratio of warm-blooded animals.

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