C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 50/18 (2006.01) C07C 225/36 (2006.01) C07F 9/09 (2006.01) C07F 9/24 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2498320
The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition.
L'invention concerne de nouveaux composés à base d'anthraquinone utiles en tant qu'extincteurs de fluorescence à spectre large et porte sur des procédés de fabrication et d'utilisation correspondants. Les extincteurs de fluorescence peuvent être conjugués à une série de composés biologiquement valables, y compris les lipides, les acides nucléiques, les polypeptides et plus particulièrement les antigènes, les stéroïdes, les vitamines, les médicaments, les haptènes, les métabolites, les toxines, les polluants, les acides aminés, les peptides, les protéines, les nucléotides, les oligonucléotides, les polynucléotides, les hydrates de carbone et leurs analogues. L'invention concerne aussi des kits comprenant dans un ou plusieurs récipients au moins une composition à base de colorant d'anthraquinone extincteur de fluorescence et des manuels d'utilisateur pour cette composition.
Behlke Mark Aaron
Huang Lingyan
Laikhter Andrei
Rose Scott
Yong Yawfui
Integrated Dna Technologies Inc.
Torys Llp
LandOfFree
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