A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/07 (2006.01) A61K 39/39 (2006.01) C07K 14/32 (2006.01)
Patent
CA 2532881
This invention provides a conjugate between poly-D-gamma glutamic acid and a carrier protein. The conjugate can be used for therapeutic or prophylactic immunization against anthrax infections. The invention also includes methods of purifying poly-D-gamma glutamic acid, methods of conjugation, vaccines and methods of vaccination against B. anthracis.
L'invention concerne un conjugué entre un acide poly-D-gamma glutamique et une protéine-support. Ce conjugué peut être utilisé pour l'immunisation thérapeutique ou prophylactique contre les infections par l'anthrax. L'invention porte également sur des méthodes de purification de l'acide poly-D-gamma glutamique, des méthodes de conjugaison, des vaccins et des méthodes de vaccination contre B.anthracis.
Caulfield Michael J.
Cook James C. III
Joyce Joseph G.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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