Anthrax vaccine formulation and uses thereof

Details Anthrax vaccine formulation and uses thereof Anthrax vaccine formulation and uses thereof

A - Human Necessities

61

K

A61K 39/07 (2006.01)

Patent

CA 2738621

An anthrax vaccine with alhydrogel as the adjuvant is presented in a composition formulated by mixing rPA with colloidal alhydrogel (alum) adjuvant to produce the final product, comprising 200 µg/ml rPA bound to 0.26% alhydrogel in phosphate buffered saline (PBS), said formulation containing an optimal concentration of phosphate. Methods of using the vaccines to treat or prevent infections are also presented.

La présente invention concerne un vaccin contre le charbon comprenant de l'Alhydrogel comme adjuvant, se présentant sous la forme d'une composition formulée par mélange de rPA avec un adjuvant Alhydrogel colloïdal (alum) pour donner un produit final comprenant 200 µg/ml de rPA lié à 0,26 % d'Alhydrogel dans un tampon phosphate salin (PBS), ladite formulation ayant une concentration optimale en phosphate. L'invention concerne également des procédés d'utilisation des vaccins pour traiter ou prévenir des infections.

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