Anti-abnormal type prion monoclonal antibody, process for...

Details Anti-abnormal type prion monoclonal antibody, process for... Anti-abnormal type prion monoclonal antibody, process for...

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2364760

A monoclonal antibody which enables to distinguish the abnormal type prior from the normal type prior, as well as production process thereof, is disclosed. The anti-abnormal type prior monoclonal antibody of the invention reacts with abnormal type prior by antigen-antibody reaction but does rat substantially react with normal type prior by antigen-antibody reaction. The anti-abnormal type prior monoclonal antibody of the invention may be obtained by immunizing an animal with an immunogen including a peptide containing a plurality of regions in the abnormal type prior, which regions are discontinuous each other in primary amino acid sequence of the abnormal type prion.

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