Anti acid-fast bacterial agent containing pyridonecarboxylic...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/56 (2006.01) A61K 31/4545 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61K 31/4995 (2006.01) A61K 31/5383 (2006.01) A61P 31/04 (2006.01) A61P 31/08 (2006.01) C07D 401/04 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01) C07D 487/08 (2006.01) C07D 498/06 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2398988

Anti-acid-fast bacterial agents containing as the active ingredient compounds represented by the general formula (1), salts thereof or hydrates of the same. Namely, pyridonecarboxylic acid derivatives having an excellent antibacterial activity on tubercle bacillus and atypical acid-fast bacteria, favorable kinetics in vivo and a high safety.

L'invention concerne des agents antibactériens acidorésistants renfermant, comme principe actif, les composés représentés par la formule générale (1) ci-après, ainsi que leurs sels ou hydrates. L'invention concerne, en particulier, des dérivés d'acide pyridonecarboxylique présentant une excellente activité antibactérienne sur le bacille de Koch et les bactéries acidorésistantes atypiques, une cinétique favorable in vivo et une grande sécurité.

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