A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/728 (2006.01) A61K 9/14 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) B05B 7/14 (2006.01) B05B 7/26 (2006.01)
Patent
CA 2559520
Dry powders containing bioresorbable hyaluraonic acid (~HA~) are applied directly to a desired location in a patient wound to reduce adhesions, without first forming a hydrated gel. HA includes hyaluronic acid that has been modified, cross-linked or combined with other substances. It is important to control the size of the particles in the powder. The powder is essentially dry and blowable powder. At least 90 % of powder particles have a maximum dimension between 30~m and 1mm.
Selon l'invention, des poudres sèches contenant de l'acide hyaluronique ( HA ) biorésorbable sont appliquées directement sur un emplacement désiré d'une plaie d'un patient afin de réduire les adhérences sans formation préalable d'un gel hydraté. HA comprend de l'acide hyaluronique modifié, réticulé ou combiné à d'autres substances. Le contrôle granulométrique est important. Cette poudre est essentiellement sèche et volatile. A u moins 90 % des particules pulvérulentes présentent une dimension maximale comprise entre 30 ?m et 1 mm.
Colt M. Jude
Greenawalt Keith E.
Kablik J. Jeffrey
Genzyme Corporation
Smart & Biggar
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