C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/99 (2006.01) C07K 14/81 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2456158
The invention provides inhibitors of matrix metalloproteinases that are useful for encouraging the development of healthy skin and for treating wounds. The inhibitors are peptides having sequences related to cleavage regions of the proenzyme forms of matrix metalloproteinases. The peptide inhibitors of the invention can be formulated into therapeutic compositions, lotions, creams, skin covering and wound dressings that facilitate healing and healthy skin development, discourage scarring and wrinkling and ameliorate the effects of healing.
L'invention concerne des inhibiteurs de métalloprotéinases matricielles qui sont utiles pour favoriser le développement d'une peau saine et pour traiter des plaies. Lesdits inhibiteurs sont des peptides dotés de séquences liées à des régions de segmentation de formes de proenzymes de métalloprotéinases matricielles. Lesdits inhibiteurs de peptides de l'invention peuvent être formulés dans des compositions thérapeutiques, des lotions, des crèmes, des produits couvrants et des pansements qui facilitent la cicatrisation ainsi que le développement d'une peau saine, empêchent la formation de cicatrices et de rides et améliorent les effets de cicatrisation.
Malik Sohail
Quirk Stephen
Villanueva Julie M.
Borden Ladner Gervais Llp
Kimberly-Clark Worldwide Inc.
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