Anti-.alpha.6-integrin-antibodies

Details Anti-.alpha.6-integrin-antibodies Anti-.alpha.6-integrin-antibodies

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12N 5/18 (2006.01) C12N 5/26 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2078817

RAN 4105/145 Abstract The present invention is directed to a monoclonal antibody or a fragment thereof which is characterized by its ability to bind to mammalian .alpha.6- integrin, preferentially human .alpha.6-integrin, and to inhibit metastasis, to a hybridoma cell line secreting such an antibody, a process for the preparation of such a hybridoma cell line and the antibody, pharmaceutical compositions containing such an antibody or a fragment thereof and the use of the antibody or a fragment thereof for the treatment of illnesses, especially cancer.

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