A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/095 (2006.01) A61P 35/00 (2006.01) C07C 323/20 (2006.01)
Patent
CA 2681267
The present disclosure relates generally to treating or preventing diseases associated with angiogenesis by administering to a patient certain compounds found to inhibit or substantially reduce angiogenesis. Compounds employed according to the present disclosure exhibit good anti-angiogenic activity as well as demonstrate a prophylactic effect for preventing and substantially reducing angiogenesis. Examples of such compounds include Ritanserin, Amiodarone, Terfenadinc, Perphenazine, Bithionol, and Clomipramine.
La présente invention concerne de façon générale le traitement ou la prévention de maladies associées à l'angiogenèse par l'administration à un patient de certains composés inhibant ou réduisant sensiblement l'angiogenèse. Les composés utilisés selon la présente invention présentent une bonne activité anti-angiogénique et démontrent un effet prophylactique permettant de prévenir ou de réduire sensiblement l'angiogenèse. Des exemples de tels composés comprennent la ritansérine, l'amiodarone, la terfénadine, la perphénazine, le bithionol, et la clomipramine.
Ananthan Subramaniam
Qu Zhican
Roy Anshu Mittal
Moffat & Co.
Southern Research Institute
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