Anti-angiogenic compositions and therapeutic applications...

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 14/03 (2006.01) A61K 38/16 (2006.01) C12N 15/38 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2727657

There is described the use of the Human herpesvirus type 6 (HHV-6) U94 gene and its product, the protein Rep, expression vectors and pharmaceutical compositions suitable for the delivery of the U94 gene or the protein encoded therefrom to the therapeutic sites, to inhibit angiogenic and lymphangiogenic processes in a subject in need thereof.

La présente invention concerne lutilisation du gène U94 de lherpesvirus humain de type 6 (HVH-6) et de son produit, la protéine Rep, des vecteurs dexpression et des compositions pharmaceutiques appropriées à la libération du gène U94 ou de la protéine codée à partir de celui-ci dans les sites thérapeutiques, pour inhiber les processus angiogéniques et lymphangiogéniques chez un patient en ayant besoin.

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