A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01)
Patent
CA 2506230
A method of using IL-6 antagonists to treat pathological processes associated with proliferative diseases, such as cancer, by specifically preventing or inhibiting the ability of new tissue to develop a blood supply. The invention more specifically relates to methods of treating such diseases by the use of IL-6 antagonists such as antibodies directed toward IL-6, including specified portions or variants, specific for at least one Interleukin-6 (IL-6 also known as interferon .beta.2) protein or fragment thereof, in an amount effective to inhibit angiogenesis.
L'invention concerne un procédé d'utilisation d'antagonistes de IL-6 pour traiter les processus pathologiques associés à des maladies prolifératives, notamment le cancer. Le procédé consiste à inhiber ou à empêcher spécifiquement la capacité d'un nouveau tissu à développer une réserve sanguine. L'invention concerne en particulier des méthodes de traitement de telles maladies faisant appel à l'utilisation d'antagonistes de IL-6, notamment des anticorps dirigés contre IL-6, y compris des parties ou des variants spécifiés, spécifiques d'au moins une protéine d'interleukine-6 (IL-6 également connu sous le nom d'interféron .beta.2) ou un fragment de celle-ci, dans une quantité efficace pour inhiber l'angiogenèse.
Trikha Mohit
Zhou Zhao
Centocor Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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