Anti-anxiety agents

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/14 (2006.01) C07D 239/42 (2006.01) C07D 401/12 (2006.01) C07D 403/14 (2006.01) C07D 413/14 (2006.01) C07D 491/08 (2006.01) C07D 491/18 (2006.01)

Patent

CA 1314881

ABSTRACT OF THE DISCLOSURE Disclosed are anti-anxiety agents 1-(heterocyclyl- carbonyl)-3-[4-(2-pyrimidlnyl)-1-piperazlnyl]propanes and 1- (heterocyclylsulfonyl)-3-[4-(2-pyrimidinyl)-1-(piperazlnyl)] propanes of the formula: Image (wherein Z is CO or SO2 and R2 is heterocyclyl group such as pyrrolidino, piperidino, piperazino, etc, optionally substituted), and methods for tlleir preparation and use.

581091

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