Anti-c35 antibody combination therapies and methods

Details Anti-c35 antibody combination therapies and methods Anti-c35 antibody combination therapies and methods

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) A61K 31/337 (2006.01) A61K 31/704 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2710680

The present invention is directed to methods of killing cancer cells, the methods comprising administering at least one C35 antibody and either at least one HER2 or at least one EGFR antibody. In some embodiments, the antibodies are administered with a therapeutic agent. The present invention is further directed to C35, HER2 and EGFR antibodies useful in these methods.

La présente invention porte sur des procédés consistant à tuer des cellules cancéreuses, les procédés comprenant l'administration d'au moins un anticorps C35 et soit d'au moins un anticorps HER2, soit d'au moins un anticorps EGFR. Dans certains modes de réalisation, les anticorps sont administrés avec un agent thérapeutique. La présente invention porte en outre sur des anticorps C35, HER2 et EGFR utiles dans ces procédés.

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