C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/22 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/24 (2006.01) C12N 15/09 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2666809
Disclosed is a monoclonal antibody having an activity of neutralizing HB-EGF. Preferably, the monoclonal antibody is an antibody incapable of binding to an HB-EGF protein located on the surface of an HB-EGF-expressing cell. Further disclosed are: a cancer therapeutic agent and a cell proliferation inhibitor, each of which comprises the monoclonal antibody as an active ingredient; and a method for treating cancer, which comprises administering the monoclonal antibody. The types of cancer which can be treated by the cancer therapeutic agent include pancreatic cancer, liver cancer, esophageal cancer, melanoma, colorectal cancer, gastric cancer, ovarian cancer, bladder cancer and brain tumor.
L'invention concerne un anticorps monoclonal ayant une activité de neutralisation de l'HB-EGF. De préférence, l'anticorps monoclonal est un anticorps incapable de se lier à une protéine HB-EGF située à la surface d'une cellule d'expression de l'HB-EGF. L'invention concerne en outre : un agent anticancéreux et un inhibiteur de la prolifération cellulaire, chacun d'eux contenant l'anticorps monoclonal en tant qu'ingrédient actif ; et un procédé destiné à traiter le cancer qui comprend l'administration de l'anticorps monoclonal. Les types de cancer qui peuvent être traités par l'agent anticancéreux incluent le cancer du pancréas, le cancer du foie, le cancer de l'oesophage, le mélanome, le cancer colorectal, le cancer de l'estomac, le cancer de l'ovaire, le cancer de la vessie et les tumeurs cérébrales.
Forerunner Pharma Research Co. Ltd.
Smart & Biggar
LandOfFree
Anti-cancer agent comprising anti-hb-egf antibody as active... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-cancer agent comprising anti-hb-egf antibody as active..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-cancer agent comprising anti-hb-egf antibody as active... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1611548