Anti-cancer antibodies against lewisb and lewis antigens

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/34 (2006.01)

Patent

CA 2663994

The present invention provides a binding complex comprising antibodies or antigen-binding fragments which bind to both Lewisy and Lewisb antigens, wherein the antibodies or antigen-binding fragments are in the form of multimers, and wherein the antibodies or antigen-binding fragments do not naturally form multimers.

La présente invention concerne un complexe de liaison comprenant des anti-corps ou des fragments de liaison à des antigènes qui se lient à la fois aux antigènes Lewisy et Lewisb, lesdits anticorps ou fragments se présentant sous la forme de multimères et les anticorps ou fragments ne formant pas naturellement de multimères.

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