Anti-cancer combination therapy

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/7068 (2006.01) A61K 31/513 (2006.01) A61K 31/7076 (2006.01)

Patent

CA 2723944

The present invention relates to a combination of therapeutic agents comprising: (a) a cytosine-based anti-cancer drug and/or a purine-based anticancer drug and (b) a therapeutic agent selected from the group consisting of thymidine phosphorylase inhibitors, and antibiotics against Mollicutes bacteria. The present invention also relates to the simultaneous, separate or sequential use of said combination for the treatment of cancer in mammals, especially in humans. The present invention also relates to methods of treatment of cancer, preferably in mammals infected with Mollicutes bacteria.

La présente invention concerne une combinaison dagents thérapeutiques comprenant : (a) un médicament contre le cancer à base de cytosine et/ou un médicament contre le cancer à base de purine et (b) un agent thérapeutique sélectionné dans un groupe constitué des inhibiteurs de la thymidine phosphorylase, et dantibiotiques agissant contre les bactéries mollicutes. La présente invention porte également sur lutilisation simultanée, séparée ou séquentielle de ladite combinaison dans le cadre du traitement du cancer chez les mammifères, et particulièrement chez lhumain. La présente invention concerne aussi des procédés de traitement du cancer, de préférence chez les mammifères atteints dune infection par les bactéries mollicutes.

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