A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01) A61K 31/475 (2006.01) A61K 31/505 (2006.01) A61K 31/65 (2006.01) A61K 31/66 (2006.01) A61K 31/70 (2006.01) A61K 33/24 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2458459
The present invention relates to synergistic combinations of the compound 5,6- dimethylxanthenone-4-acetic acid (DMXAA) and a compound selected from platinum compounds, vinca alkaloids, alkylating agents, anthracyclines, topoisomerase I inhibitors, antimetabolites and topoisomerase II inhibitors, which have anti- tumour activity. More particularly, the invention is concerned with the use of such combinations in the treatment of cancer and pharmaceutical compounds containing said combinations.
L'invention concerne des combinaisons synergistiques du composé d'acide 5,6-dimethylxanthenone-4-acétique (DMXAA) et d'un composé sélectionné dans le groupe constitué par des composés de platine, des alcaloïdes vinca, des agents d'alkylation, des anthracyclines, des inhibiteurs de la topoisomérase I, des antimétabolites et des inhibiteurs de la topoisomérase II, présentant une activité antitumorale. L'invention concerne, plus particulièrement, l'utilisation de ces combinaisons pour traiter le cancer et des compositions pharmaceutiques renfermant lesdites combinaisons.
Siim Bronwyn Gae
Wilson William Robert
Cancer Research Technology Limited
Sim & Mcburney
LandOfFree
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