Anti-cancer composition comprising microrna molecules

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/7105 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) C12N 15/113 (2010.01) A61K 48/00 (2006.01)

Patent

CA 2690838

Disclosed is an anticancer composition for the treatment of hypoxia-induced angiogenesis-associated diseases including cancers. It comprises a microRNA-125 nucleic acid molecule. Also, methods of inhibiting angiogenesis, suppressing the invasion and metastasis of cancer cells, and treating cancers are provided.

L'invention porte sur une composition anti-cancer pour le traitement de maladies associées à une angiogenèse induite par hypoxie comprenant des cancers. Elle comprend une molécule d'acide nucléique de micro ARN-125. L'invention porte également sur des procédés d'inhibition de l'angiogenèse, de suppression de l'invasion et de formation de métastases des cellules cancéreuses et de traitement des cancers.

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