Anti-cancer drugs and uses relating thereto for metastatic...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 333/38 (2006.01) A61K 31/381 (2006.01) A61P 35/00 (2006.01) C07D 333/40 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2736732

The present invention discloses triazene analogs of the general formula (I) and formula (II), their tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts thereof for the metastatic malignant melanoma and other cancers including but not limited to lymphomas, sarcomas, carcinomas, and gliomas. The invention further discloses a process for the preparation of the above said triazene analogs of formula (I) and formula (II), and their pharmaceutically acceptable compositions.

La présente invention concerne des analogues du triazène de formule générale (I) et de formule (II), leurs formes tautomères, stéréoisomères, polymorphes, hydrates, solvates, et sels pharmaceutiquement acceptables contre le mélanome malin métastatique et d'autres cancers comprenant mais non limités aux lymphomes, sarcomes, carcinomes, et gliomes. L'invention concerne en outre un procédé de préparation desdits analogues du triazène décrits ci-dessus de formule (I) et de formule (II), et leurs compositions pharmaceutiquement acceptables.

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