C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/4152 (2006.01) A61K 31/4184 (2006.01) A61K 31/433 (2006.01) A61K 31/506 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2511840
Novel compounds and methods of using those compounds for the treatment of oncological conditions are provided. In a preferred embodiment, modulation of the activation states of abl or bcr-abl .alpha.-kinase proteins comprises the step of contacting the kinase proteins with the novel compounds.
L'invention concerne des nouveaux composés ainsi que des méthodes consistant à utiliser ces composés pour traiter des affections oncologiques. Dans un mode de réalisation privilégié, la modulation de l'activation des états des protéines abl ou bcr-abl ?-kinase, consiste à mettre en contact les protéines kinases avec les nouveaux composés.
Flynn Daniel L.
Petillo Peter A.
Deciphera Pharmaceuticals Llc
Gowling Lafleur Henderson Llp
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