Anti-cancer therapy comprising an h2-blocker, at least one...

A - Human Necessities – 61 – K

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Details

A61K 31/675 (2006.01) A61K 31/196 (2006.01) A61K 31/203 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/4402 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2656910

The present invention relates to the treatment of a mammal with a pharmaceutical composition comprising an H2-blocker, at least one anti-inflammatory agent, a cytotoxic agent and, optionally, levamisole, a retinoid, an NFkB inhibitor, a redox quinone, an agent that enhances the intracellular accumulation of NADH + H+, a poly-alcohol, an inhibitor of pro-angiogenic growth factor(s) and an MMP inhibitor, such pharmaceutical composition allowing for the enhanced therapy and/or prevention of neoplastic diseases and disorders.

La présente invention concerne le traitement d'un mammifère au moyen d'une composition pharmaceutique comprenant un H2-bloquant, au moins un agent anti-inflammatoire, un agent cytotoxique et, éventuellement, du lévamisole, un rétinoïde, un inhibiteur de NF.kappa.B, une quinone redox, un agent renforçant l'accumulation intracellulaire de NADH + H+, un polyalcool, un inhibiteur d'un ou plusieurs facteurs de croissance pro-angiogéniques et un inhibiteur de MMP, cette composition pharmaceutique permettant d'améliorer le traitement et/ou la prévention de maladies et de troubles néoplasiques.

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