A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 35/12 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61K 48/00 (2006.01) A61K 31/7084 (2006.01) A61K 38/44 (2006.01) A61K 38/50 (2006.01)
Patent
CA 2536654
The present provides tumor-associated HLA-restricted antigens, and in particular HLA-~A2 restricted antigens, as vaccines for treating or preventing cancers in a patient. In specific aspects, there is proteinase 3 peptides are provided. Such peptides can be used to elicit specific CTLs that preferentially attack myeloid leukemia based on overexpression of the target protein cells.
L'invention porte sur des antigènes associés aux tumeurs à HLA restreinte et en particulier à HLA-A2 restreinte, pouvant servir de vaccins pour le traitement ou la prévention de cancers, et selon certains aspects, de peptides de protéinase 3 pouvant susciter des cellules T tueuses s'attaquant préférentiellement aux leucémies myéloïdes suite à une surexpression des cellules protéiques cibles.
Barrett John A.
Molldrem Jeffrey
Bcf Llp
Board Of Regents The University Of Texas System
Department Of Health And Human Services Government Of The United States Of America As Represented By Sec
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