A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 51/00 (2006.01) C07K 16/00 (2006.01) C07K 16/46 (2006.01)
Patent
CA 2534639
The present invention provides humanized, chimeric and human anti-CD19 antibodies, anti-CD19 antibody fusion proteins, and fragments thereof that bind to a human B cell marker. Such antibodies, fusion proteins and fragments thereof are useful for the treatment and diagnosis of various B-cell disorders, including B-cell malignancies and autoimmune diseases.
La présente invention concerne des anticorps anti-CD19 humains, chimériques et humanisés, des protéines hybrides d'anticorps anti-CD19, et des fragments de ceux-ci se liant à un marqueur de lymphocyte B humain. Ces anticorps, ces protéines hybrides et ces fragments sont particulièrement utiles pour traiter et diagnostiquer divers troubles liés aux lymphocytes B, y compris la malignité des lymphocytes B et les maladies auto-immunes.
Goldenberg David M.
Hansen Hans J.
Qu Zhengxing
Immunomedics Inc.
Smart & Biggar
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