Anti-cd19 antibodies with reduced immunogenicity

Details Anti-cd19 antibodies with reduced immunogenicity Anti-cd19 antibodies with reduced immunogenicity

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C12N 15/10 (2006.01) C12N 15/13 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2635623

Anti-CD19 B4 antibodies with modified variable regions are disclosed. The modified anti-CD19 variable region polypeptides have alterations to one or more framework regions or complementarity determining regions of the heavy chain variable region or light chain variable region, thereby to reduce a T- cell response.

La présente invention a pour objet des anticorps B4 anti-CD19 dont les régions variables sont modifiées. Les polypeptides anti-CD19 dont les régions variables sont modifiées présentent des altérations au niveau d'une ou de plusieurs régions de la structure principale ou de régions déterminant la complémentarité de la région variable de la chaîne lourde ou de la région variable de la chaîne légère, ceci afin de réduire la réponse des cellules T.

Affiliated with

Also associated with

Rating

Anti-cd19 antibodies with reduced immunogenicity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-cd19 antibodies with reduced immunogenicity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-cd19 antibodies with reduced immunogenicity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1927317