Anti-cd20 antibodies and fusion proteins thereof and methods...

Details Anti-cd20 antibodies and fusion proteins thereof and methods... Anti-cd20 antibodies and fusion proteins thereof and methods...

C - Chemistry, Metallurgy

07

K

C07K 16/46 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) A61P 35/02 (2006.01) A61P 37/00 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 15/13 (2006.01) C12N 15/62 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2476166

The present invention provides humanized, chimeric and human anti-CD20 antibodies and CD 20 antibody fusion proteins that bind to a human B cell marker, referred to as CD20, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies and autoimmune diseases, and methods of treatment and diagnosis.

La présente invention concerne des anticorps anti-CD20 humanisés, chimères ou humains, et des protéines hybrides des anticorps anti-CD20 qui se lient à un marqueur de cellules B humaines, appelé CD20, utile pour le traitement ou le diagnostic de troubles induits par des cellules B, tels que la malignité de cellules B. L'invention concerne en outre des méthodes de traitement ou de diagnostic.

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