Anti-cd20 therapeutic compositions and methods

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/46 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2691322

The present invention provides materials and methods for treatment of diseases involving aberrant B-cell activity, using a CD20-specific binding molecule, in particular, antibodies or antigen binding fragment thereof. The compositions disclosed herein is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies and autoimmune diseases.

La présente invention porte sur des matières et des procédés pour le traitement de maladies mettant en jeu une activité aberrante des lymphocytes B, à l'aide d'une molécule de liaison spécifique à CD-20, en particulier, des anticorps ou un fragment de liaison à un antigène de ceux-ci. Les compositions décrites ici sont utiles pour le traitement et le diagnostic de troubles des lymphocytes B, tels que des tumeurs malignes de lymphocytes B et des maladies auto-immunes.

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