C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01)
Patent
CA 2569509
The present invention is related to antibodies directed to the antigen CD3 and uses of such antibodies. In particular, the present invention provides fully human monoclonal antibodies directed to CD3. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR~s), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
La présente invention concerne des anticorps dirigés contre l'antigène CD3 et leurs utilisations. Notamment, cette invention a trait à des anticorps monoclonaux entièrement humains dirigés contre CD3. Ladite invention a également pour objet le codage de séquences de nucléotides et des séquences d'acides aminés contenant des molécules d'immunoglobines à chaînes lourde et légère, plus spécifiquement, des séquences correspondant à des séquences à chaînes lourde et légère contigües qui étalent les régions de structure et/ou les régions de détermination de la complémentarité (CDR's), particulièrement de FR1 par FR4 ou de CDR1 par CDR3. L'invention concerne aussi des hybridomes ou d'autres lignées cellulaires exprimant de telles molécules d'immunoglobines et des anticorps monoclonaux.
Dean Yann
Elson Greg Christopher Andrew
Fischer Nicolas
Kosco-Vilbois Marie
Leger Olivier
Novimmune S.a.
Ridout & Maybee Llp
LandOfFree
Anti-cd3 antibodies and methods of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-cd3 antibodies and methods of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-cd3 antibodies and methods of use thereof will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1718404