Anti-cd40 monoclonal antibody

Details Anti-cd40 monoclonal antibody Anti-cd40 monoclonal antibody

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01)

Patent

CA 2658221

Disclosed are an antibody or a functional fragment thereof that recognize human CD40 antigen present on a surface of human B cells and human dendritic cells. The antibody has amino acid sequences of a heavy chain variable region and a light chain variable region of antibody produced by hybridoma 4D11. The antibody is useful, for example, as immunosuppressive agent, for treating autoimmune disease or the like.

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