A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12N 15/13 (2006.01)
Patent
CA 2467597
Antibodies which specifically recognize the human CD45 isoform RB are presented. These antibodies may be used to block undesirable immune reactions in patients with transplant rejection and autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and autoimmune diabetes.
L'invention a trait à des anticorps reconnaissant en particulier l'isoforme RB de CD45 humain. Ces anticorps peuvent être utilisés pour bloquer les réponses immunitaires non souhaitables de rejet du greffon survenant chez des patients, ainsi que des maladies auto-immunes telles que la polyarthrite rhumatoïde, la sclérose en plaques et le diabète insulino-dépendant.
Babcook John
Foltz Ian
King Chadwick T.
Palathumpat Varghese
Yang Xiao-Dong
Abgenix Inc.
Smart & Biggar
LandOfFree
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